"Men ought to know that from nothing else but the brain come, joys, delights, laughter, and sports, and sorrows, grief’s, despondency, and lamentations, And by this, in an especial manner, we acquire wisdom and knowledge, and see, and hear, and know what are foul and what are fair, what are bad and what are good, what are sweet and what are unsavory, and by the same organ, we become mad and delirious , and fears and terrors assail us, … All these thing’s we endure from the brain."
From "On the Sacred Disease" By Hippocrates, 5th Century B.C.
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